Who are we?

The Brumback Lab aims to understand the neurophysiological mechanisms of autism & related neurodevelopmental conditions. Our long-term goal is to develop neuromodulation therapies for specific neuropsychiatric symptoms that localize to the prefrontal network. We use experimental approaches such as brain slice patch clamp recordings, in vivo extracellular electrophysiology and calcium imaging, and in vivo optogenetics combined with animal behavioral assays.

Our Research Techniques

  • Optogenetics

    The activation or inhibition of specific populations of neurons using light.

  • Whole-cell Patch Clamp Electrophysiology

    Measuring the electrical activity of single neurons in real time.

  • Behavioral Assays

    Observation of behaviors that mice exhibit in different settings.

Our Affiliates